Ku­ra flash­es pos­i­tive HRAS da­ta on once-failed J&J drug

Troy Wil­son was work­ing with J&J on their KRAS in­hibitor and pe­ri­od­i­cal­ly thumb­ing through their pub­li­ca­tions when he spot­ted an old drug called tip­i­farnib that looked promis­ing. So promis­ing, in fact, that the large phar­ma had run it through over 5,000 pa­tients across 70 tri­als, hop­ing they would at some point be able to nail down who were the small slice of pa­tients who re­spond­ed in some stud­ies.

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