Men­lo’s IPO hang­over be­gins with a failed PhII for an old Mer­ck castoff

Just a lit­tle more than two months af­ter Men­lo Ther­a­peu­tics went pub­lic $MN­LO, rais­ing $119 mil­lion from a suc­cess­ful IPO in the midst of a rol­lick­ing good time on Wall Street for high risk of­fer­ings, their one and on­ly drug in the clin­ic just de­ci­sive­ly failed a Phase II tri­al.

In­ves­ti­ga­tors say that ser­lop­i­tant failed to dis­tin­guish it­self from a place­bo in a pru­ri­tus study with 484 pa­tients, flunk­ing the pri­ma­ry and key sec­ondary end­points. Ex­ecs for the com­pa­ny, though, are vow­ing to hang on, not­ing some ear­li­er pos­i­tive mid-stage da­ta as well as a Phase III that is about to launch.

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