Mi­cro­bio­me Q&A: New study maps the vagi­na's 'op­ti­mal mi­cro­bio­ta' — and its im­pli­ca­tions for bio­phar­ma

The wide­ly-held no­tion that the “op­ti­mal” vagi­nal mi­cro­bio­ta is dom­i­nat­ed by one strain of lac­tic-acid pro­duc­ing bac­te­ria has now been chal­lenged in a new pa­per, pub­lished in Na­ture Com­mu­ni­ca­tions on Wednes­day, which used ad­vanced gene se­quenc­ing meth­ods to map out the most com­pre­hen­sive gene cat­a­log of the hu­man vagi­nal mi­cro­bio­me.

Things have changed in the more than 50 years since the con­cept of vagi­nal mi­cro­bio­ta trans­plants was pro­posed and sub­se­quent­ly taint­ed by a Texas-based gy­ne­col­o­gist who trans­plant­ed the vagi­nal flu­id of women who had bac­te­r­i­al vagi­nosis in­to healthy fe­males, sus­pect­ing he had iso­lat­ed the bac­te­ria re­spon­si­ble for the con­di­tion.

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.