MIT lab cre­ates tool to find can­cer mu­ta­tion dri­vers 'any­where in the genome'

Pre­ci­sion on­col­o­gy has been her­ald­ed as the way for­ward in treat­ing can­cer, but search­ing for dri­ver mu­ta­tions has com­pli­cat­ed that jour­ney as ex­ist­ing meth­ods can’t be ap­plied to the en­tire genome.

But a new method out of MIT looks to change the way can­cer dri­ver mu­ta­tions are found and, in do­ing so, speed up the process. A group out of Bon­nie Berg­er’s lab at the in­sti­tu­tion has de­vel­oped what they named “Dig,” an in­ter­ac­tive map for find­ing dri­ver el­e­ments and mu­ta­tions “any­where in the genome,” ac­cord­ing to a pa­per pub­lished this week in Na­ture Biotech­nol­o­gy.

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