Neil Woodford. Woodford Investment Management via YouTube

Neil Wood­ford re­fresh­es port­fo­lio with fire sale while in­vestors pon­der fu­ture of sus­pend­ed fund

Ahead of an ex­pect­ed up­date on the sus­pen­sion of his flag­ship fund, Neil Wood­ford has re­port­ed­ly raised £459 mil­lion from share sales across his port­fo­lio of funds, City­wire re­ports.

The in­vest­ment man­age­ment firm is hold­ing some of it in cash while putting the rest to use in oth­er stocks, a spokesper­son told Bloomberg — which counts at least £300 mil­lion ($379 mil­lion) in sales from the frozen Eq­ui­ty In­come Fund. Sell­ing off illiq­uid or un­list­ed as­sets is key to Wood­ford’s turn­around mis­sion for the fund, which was suf­fer­ing from an ex­o­dus of in­vestors that shrunk the fund from £10.2 bil­lion to £3.7 bil­lion in two years and squeezed its abil­i­ty to meet any fur­ther re­demp­tions.

“We haven’t dis­put­ed the City­wire or Bloomberg sto­ries, but we do not pro­vide con­fir­ma­tion of every sale or stock bought by Wood­ford,” a spokesper­son told me in re­sponse to a query. “The de­ci­sion on sus­pen­sion is made by Link, the ACD for the fund, and I be­lieve they are plan­ning to make an an­nounce­ment lat­er to­day.”

Link Fund So­lu­tions is tech­ni­cal­ly the “au­tho­rized cor­po­rate di­rec­tor” that del­e­gat­ed Wood­ford’s firm to man­age its funds.

Af­ter abrupt­ly no­ti­fy­ing in­vestors that they would not be al­lowed to re­deem, sell, trans­fer or can­cel their shares in the Wood­ford Eq­ui­ty In­come Fund for at least 28 days, Wood­ford ex­plained that he need­ed the time and re­sources to re­bal­ance the port­fo­lio. To­day marks the end of that four-week time­frame.

Through pub­lic fil­ings and da­ta, Bloomberg found that since dis­clos­ing the dras­tic mea­sure in June, he has sold shares in BCA Mar­ket­place, NewRiv­er RE­IT and Oak­ley Cap­i­tal In­vest­ments, among oth­er po­si­tions.

On top of that, he’s al­so of­floaded stakes in Mereo Bio­phar­ma, e-Ther­a­peu­tics and Sen­syne Health, ac­cord­ing to City­wire. Some sales had ap­par­ent­ly come from the Wood­ford In­come Fo­cus Fund, which is still open and has lost in­vestors de­spite Wood­ford’s best ef­forts. The Pa­tient Cap­i­tal Trust is al­so ex­plor­ing sales af­ter trad­ing down al­most 30% on the Lon­don Stock Ex­change, in part to help cut bor­row­ing.

Days ago, UK fi­nan­cial reg­u­la­tors say they are now tak­ing a hard look in­to the sus­pen­sion of the Eq­ui­ty Fund. How Wood­ford man­aged the liq­uid­i­ty of the fund will like­ly be the cen­ter of the Fi­nan­cial Con­duct Au­thor­i­ty’s scruti­ny.

As in­vestors anx­ious­ly await an up­date, the Times is re­port­ing that Link plans to con­tin­ue the sus­pen­sion in­def­i­nite­ly be­cause they deem the Eq­ui­ty Fund un­pre­pared for the flood of ex­pect­ed re­demp­tion re­quests.

We will be watch­ing for the of­fi­cial re­lease when it drops.

Nick Galakatos, Blackstone global head of life sciences

Nick Galakatos and the Black­stone team now have a record $4.6B to in­vest in bio­phar­ma, with a big fo­cus on push­ing com­pa­nies over the top

Nick Galakatos and his team at Blackstone Life Sciences have seen their biggest opportunities swell up in mostly established players who don’t have all the money they need to accomplish everything on the to-do list. And right now, with the industry booming, that’s a long list with some hefty needs.

The Blackstone team has neatly tied up the largest private fund ever raised in life sciences for making big dreams come true in biopharma. Late Thursday, Blackstone put out word that they had closed their highly anticipated fund with the projected $4.6 billion all in.

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UP­DAT­ED: Bio­gen shares spike as ex­ecs com­plete a de­layed pitch for their con­tro­ver­sial Alzheimer's drug — the next move be­longs to the FDA

Biogen is stepping out onto the high wire today, reporting that the team working on the controversial Alzheimer’s drug aducanumab has now completed their submission to the FDA. And they want the agency to bless it with a priority review that would cut the agency’s decision-making time to a mere 6 months.

The news drove a 10% spike in Biogen’s stock $BIIB ahead of the bell.

Part of that spike can be attributed to a relief rally. Biogen execs rattled backers and a host of analysts earlier in the year when they unexpectedly delayed their filing to the third quarter. That delay provoked all manner of speculation after CEO Michel Vounatsos and R&D chief Al Sandrock failed to persuade influential observers that the pandemic and other factors had slowed the timeline for filing. Actually making the pitch at least satisfies skeptics that the FDA was not likely pushing back as Biogen was pushing in. From the start, Biogen execs claimed that they were doing everything in cooperation with the FDA, saying that regulators had signaled their interest in reviewing the submission.

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Gilead boasts of pos­i­tive remde­sivir da­ta on mor­tal­i­ty — but their analy­sis pro­vokes the skep­tics

Gilead is surging again off data that suggest its antiviral remdesivir might improve survival.

The new data come from an analysis Gilead conducted comparing the death rate and recovery time of patients in one of its remdesivir trials to a group of 800 patients “with similar baseline characteristics and disease severity” who received only standard-of-care around the same time. The result, they said, suggested that patients who received remdesivir had a 62% better chance at surviving than those who did not.

Hal Barron, GSK

Win or lose on the mar­ket­ing OK, the FDA just gunned down GSK’s bright hopes for their BC­MA ther­a­py

The FDA’s ODAC — the Oncologic Drugs Advisory Committee — has a well-known bias in favor of adding new cancer drugs to the market, even if efficacy is at best marginal and serious safety issues demand careful management.

Doctors want as many arrows in their quiver as they can get. And when patients are dying after failing multiple drugs, why not give it a go one more time?

GlaxoSmithKline, though, is about to test out how their new BCMA antibody drug conjugate belantamab mafodotin can do after being mauled in an in-house FDA review, ahead of the Tuesday expert panel discussion. Even if the agency goes ahead with an expected green light, this drug will likely be constrained to a small niche — icing any plans they may have for making waves in oncology anytime soon.

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Covid-19 roundup: BioN­Tech go­ing head-to-head with Mod­er­na as PhI­II mR­NA launch looms; Tri­al on Shin­zo Abe’s once-fa­vorite an­tivi­ral is in­con­clu­sive

It’s a race to the Phase III finish line now for the 2 leading mRNA vaccines in the pipeline for Covid-19.

BioNTech chief Ugur Sahin told the Wall Street Journal that his company will start Phase III testing of their vaccine later this month, setting them up to lateral the data to regulators before the end of this year.

That puts them essentially on the exact same schedule as Moderna is dedicated to. The Massachusetts rival to BioNTech also expects to launch Phase III this month. Lots of rumors have circulated about delays and conflict among the scientists advancing the Moderna jab, but the biotech has consistently stuck to its plan to start a late-stage pivotal this month.

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Stephan Christgau, Amanda Hayward, Andreas Segerros and Magnus Persson (Eir Ventures)

A new ven­ture fund amid a pan­dem­ic? In the Nordics? Eir Ven­tures brings it on with €76M first close

From Pharmacia and Lundbeck to Novo Nordisk and AstraZeneca, the Nordic countries have been the birthplace for some legacy pharma companies. But for all that history and reputation, Stephan Christgau counts only five specialized life science investors backing biotechs today.

That leaves plenty of room for Eir Ventures, a brand new venture fund Christgau — one of the founders of Novo Seeds — is launching with three other veteran VCs.

Regeneron CEO Leonard Schleifer speaks at a meeting with President Donald Trump, members of the Coronavirus Task Force, and pharmaceutical executives in the Cabinet Room of the White House (AP Photo/Andrew Harnik)

OWS shifts spot­light to drugs to fight Covid-19, hand­ing Re­gen­eron $450M to be­gin large scale man­u­fac­tur­ing in the US

The US government is on a spending spree. And after committing billions to vaccines defense operations are now doling out more of the big bucks through Operation Warp Speed to back a rapid flip of a drug into the market to stop Covid-19 from ravaging patients — possibly inside of 2 months.

The beneficiary this morning is Regeneron, the big biotech engaged in a frenzied race to develop an antibody cocktail called REGN-COV2 that just started a late-stage program to prove its worth in fighting the virus. BARDA and the Department of Defense are awarding Regeneron a $450 million contract to cover bulk delivery of the cocktail starting as early as late summer, with money added for fill/finish and storage activities.

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Atul Deshpande, Harbour BioMed chief strategy officer & head, US operations (Harbour BioMed)

An­oth­er biotech IPO set-up? Multi­na­tion­al biotech leaps from round to round, scoop­ing up cash at a blis­ter­ing pace

A short four months after announcing a $75 million haul in Series B+ fundraising, the multinational biotech Harbour BioMed pulled in another round of investments and eclipsed the nine-digit mark in the process.

Harbour completed its Series C financing, the company announced Thursday morning, raising $102.8 million and bringing its total investment sum to over $300 million since its founding in late 2016. The biotech plans to use the money to transition early-stage candidates from the discovery phase, fund candidates already in the clinic, and prep late-stage candidates for commercialization.

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Ed Engleman (Stanford Blood Center)

Stan­ford star on­col­o­gy sci­en­tist Ed En­gle­man helped cre­ate the im­munother­a­py field. Now he wants to shake up neu­rode­gen­er­a­tion R&D

Over the last generation of drug R&D, Ed Engleman has been a standout scientist.

The Stanford professor co-founded Dendreon and provided the scientific insights needed to develop Provenge into a pioneering — though not particularly marketable — immunotherapy. He’s spurred a slate of startups, assisted by his well-connected perch as a co-founder of Vivo Capital, and took the dendritic cell story into its next chapter at a startup called Bolt.

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