NeuExcell strikes deal with Fujifilm for stroke gene therapy; J&J expands in Ireland
In an effort to advance a gene therapy to treat ischemic cortical stroke, Fujifilm Diosynth Biotechnologies and NeuExcell Therapeutics have reached an agreement to produce drug substance in College Station, TX.
Fujifilm will do so under an accelerated timeline for NeuExcell’s first-in-human clinical studies of NXL-001.
Gerry Farrell, the COO of Fujifilm, says that the deal shows the company is able to work with companies of all sizes.
“We are proud and delighted to have been selected by NeuExcell as the manufacturing partner for their NXL-001 candidate. It is an honor for FDB to play a role helping to bring a treatment to patients around the world who suffer from ischemic cortical stroke,” he said in a statement.”
NeuExcell is based out of Pennsylvania and is focused on neurodegenerative diseases and the central nervous system. Its pipeline has investigational therapies for stroke, Huntington’s disease, ALS, Alzheimer’s and Parkinson’s disease.
Fujifilm has established itself as a key player in the gene therapy production plan, as it doled out $850 million in July into US and UK locations to increase capacity. Those expansions will start in 2023, and brought the total amount of money invested in its CDMO wing to $5.5 billion in the past 10 years, including a $76 million increase into its Watertown, MA site that includes eight cleanrooms and 40,000 square feet to be opened in 2022. It also opened a $2 billion plant in Holly Springs, NC, set to be operational by 2025.
J&J expands in Ireland
About 180 new jobs are coming to Cork, Ireland, as J&J has announced the expansion of its manufacturing site that’s been in operation since 2005.
The company has submitted an application for a €150 million expansion in Ringaskiddy that will up the size by 8,202 square feet. The site is dedicated to manufacturing products that treat rheumatoid arthritis, psoriasis and cancer, though it isn’t clear exactly which drugs are manufactured there.
J&J finished an expansion at the site in 2019, adding more than 205,000 square feet of capacity and another 200 jobs.