CBER Director Peter Marks (Jim Lo Scalzo/Pool via AP Images)

Next-gen Covid vac­cines: No more quick vari­ant up­dates and RCTs may be re­quired, CBER leader writes

Gone are the days of Covid-19 vac­cine de­vel­op­ers promis­ing to quick­ly shift their mR­NA vac­cines to tar­get the next vari­ant every three to four months.

Now, CBER Di­rec­tor Pe­ter Marks is call­ing on the Mod­er­nas and BioN­Tech/Pfiz­ers of the world to re­al­ly start con­sid­er­ing to de­vel­op a “dis­tinct­ly im­proved gen­er­a­tion of SARS-CoV-2 vac­cines of­fer­ing longer pro­tec­tion with greater scope.”

Writ­ing in a JA­MA view­point yes­ter­day, Marks and two coau­thors from Brown Uni­ver­si­ty’s med­ical school made clear that:

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