No­var­tis-backed In­fla­zome rais­es $46M for their clin­i­cal chal­lenge to prove NL­RP3 is a great an­ti-in­flam­ma­to­ry tar­get

The big CAN­TOS study may not have pro­duced the block­buster ap­proval that No­var­tis had been promis­ing in car­dio, but its suc­cess in the IL-1 be­ta path­way has helped in­spire a slate of star­tups that are mov­ing up­stream to what’s be­come a hot field in NL­RP3 in­hi­bi­tion.

To­day’s sto­ry cen­ters on In­fla­zome, which de­scribes it­self as one of the pi­o­neers in NL­RP3. The biotech has raised $46 mil­lion for its Se­ries B round to shift out of pre­clin­i­cal work and head straight in­to the clin­ic next year, with plans to tee up a safe­ty study fol­lowed by a for­ay in­to an or­phan CNS con­di­tion.

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