Vas Narasimhan, Novartis CEO (Thibault Camus/AP Images)

No­var­tis' first at­tempt to repli­cate a stun­ning can­cer re­sult falls flat

A decade ago, No­var­tis launched a 10,000-per­son tri­al to try to turn a rare dis­ease drug in­to the next heart dis­ease block­buster. In 2017, the study ul­ti­mate­ly failed to show enough car­dio­vas­cu­lar ben­e­fit to win over reg­u­la­tors, but in the process, No­var­tis found a sur­pris­ing and in­trigu­ing bit of da­ta: Pa­tients who re­ceived the drug were 77% less like­ly to die of lung can­cer than those who didn’t.

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