No­var­tis says its Soliris add-on might be able to re­place the Alex­ion drug al­to­geth­er. But is it too late?

No­var­tis says one of its top emerg­ing drugs spot­light­ed by Vas Narasimhan has come through in a Phase II tri­al for parox­ys­mal noc­tur­nal he­mo­glo­bin­uria, bur­nish­ing its prospect as an add-on — or even al­ter­na­tive — to Alex­ion’s Soliris.

Go­ing af­ter the al­ter­na­tive com­ple­ment path­way, the phar­ma gi­ant sees oral ad­min­is­tra­tion as one of LNP023’s key at­trac­tions — al­though an­a­lysts say it’s too late to make much of a dif­fer­ence in this par­tic­u­lar rare blood dis­or­der.

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