No­var­tis team scores a pi­o­neer­ing first in car­dio R&D. But can they sell it?

No­var­tis is fac­ing an­oth­er block­buster chal­lenge of glob­al pro­por­tions.

How do you mar­ket a heart drug with re­al but clear­ly lim­it­ed health ben­e­fits? One where there’s no es­tab­lished abil­i­ty to se­ri­ous­ly cut down the rate of death — and head­ed to a field where pay­ers are skilled at stand­ing be­tween pa­tients and high-cost PC­SK9 drugs?

That’s the sit­u­a­tion for No­var­tis as it takes its da­ta on canakinum­ab to the FDA and reg­u­la­tors around the world.

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