On a mis­sion to make or­gan trans­plants safer and more durable, Black­stone gifts Ta­laris a new CEO, leads $100M round

As a trans­plant sur­geon by train­ing, Suzanne Ild­stad un­der­stood the plight of her pa­tients all too well: The risk of or­gan re­jec­tion forces them to adopt im­muno­sup­pres­sion reg­i­mens, which in turn ex­pose them to in­fec­tions and car­dio­vas­cu­lar prob­lems they have to con­tend with. She knew that if the bone mar­row from a donor takes, any sub­se­quent or­gan trans­plant would, too.

“We dis­cov­ered a cell in the bone mar­row called the fa­cil­i­tat­ing cells that is CD8 pos­i­tive and T cell re­cep­tor neg­a­tive, and it helps the stem cell to take,” Ild­stad, di­rec­tor of the Uni­ver­si­ty of Louisville’s In­sti­tute of Cell Ther­a­py, said. “From that we de­vel­oped a method to process the bone mar­rows from hu­mans to es­sen­tial­ly take out the bad cells and leave in the good cells.”

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