Steve Harr (L) and Hans Bishop

One of the most am­bi­tious start­up teams in biotech just out­lined plans for a $400M IPO and a val­u­a­tion of about $4B

The ex­ec­u­tive team at Sana Biotech­nol­o­gy has sketched out more de­tails about the full scope of its am­bi­tions as the new uni­corn to watch. They amend­ed their S-1 to­day to in­clude a price range of $20 to $23 a share — which puts them in reach of pulling in around $400 mil­lion on the high end with a mar­ket val­ue start­ing right around $4 bil­lion.

That’s not bad for a pre­clin­i­cal biotech with no drugs yet in hu­man stud­ies, but it squares with its am­bi­tions to re­make the cell ther­a­py field with a slate of in-house plat­forms. The biotech raised $705 mil­lion — pri­mar­i­ly from ARCH (44 mil­lion shares) and Flag­ship (34.2 mil­lion shares) — to get to this stage.

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