Mark Smith, Finch Therapeutics CEO

One week af­ter Take­da walked away, Finch faces sec­ond round of lay­offs, pipeline prun­ing

Finch may be an inch un­der­ground at this point.

Somerville, MA-based Finch Ther­a­peu­tics has had a rough year, start­ing with the FDA slap­ping a clin­i­cal hold on its late-stage C. dif­fi­cile treat­ment in March. While that hold was lift­ed at the end of April, it had al­ready tak­en its toll, with Finch lay­ing off 37 of its work­ers and cut­ting its he­pati­tis B pro­gram in the in­ter­im.

Then, last week, Take­da end­ed its five-year al­liance with the biotech, giv­ing back glob­al rights to two pre­clin­i­cal pro­grams in ul­cer­a­tive col­i­tis and Crohn’s dis­ease. In re­ac­tion to that, Finch is lay­ing off an ad­di­tion­al 50 em­ploy­ees, about an­oth­er third of its work­force, ac­cord­ing to an SEC fil­ing this morn­ing.

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