Ulrik Mouritzen, Breye CEO

Oral al­ter­na­tive to eye in­jec­tions? No­vo backs start­up’s big plan to re­pur­pose shelved drug

For pa­tients with di­a­bet­ic retinopa­thy, an­ti-VEGF in­jec­tions to the eye are of­ten the on­ly non-sur­gi­cal op­tion to stave off vi­sion loss. But in re­cent years, sev­er­al Big Phar­ma play­ers — in­clud­ing Roche and Bay­er — are be­gin­ning to test drugs that can be giv­en oral­ly.

A biotech start­up out of Copen­hagen wants to give them a run for their mon­ey.

Found­ed by No­vo Seeds, Br­eye Ther­a­peu­tics (rhymes with “eye”) is com­ing out of the gate with $4 mil­lion in seed fund­ing from No­vo Hold­ings and Sound Bioven­tures. Its lead drug comes from Zealand Phar­ma, where Br­eye CEO Ul­rik Mouritzen served as head of clin­i­cal de­vel­op­ment be­fore launch­ing the new com­pa­ny in 2019.

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