Out to chal­lenge Gilead­'s dai­ly pills, Vi­iv scores three-year da­ta on month­ly com­bo; Rigel bags $33M from Asia li­cens­ing deal

→ On the heels of an NDA sub­mis­sion, Vi­iv has post­ed longterm da­ta sup­port­ing its the­o­ry that an­oth­er one of its long-act­ing two-drug com­bos could work just as well as the dai­ly triplets of­fered by its big ri­val Gilead. In a Phase IIb tri­al, re­searchers found that at the three-year mark, 90% pa­tients re­ceiv­ing the in­jectable reg­i­men of cabote­gravir and rilpivirine every eight weeks re­mained vi­ral­ly sup­pressed; 83% of those on the four-week reg­i­men did. It echoes a set of Phase III re­sults the GSK sub­sidiary un­veiled in Au­gust, which Vi­iv says points to the com­bo’s po­ten­tial in “chang­ing HIV treat­ment from 365 dos­ing days per year, to just 12.”

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