Penn scientists correct genetic flaw in mice fetuses, expanding in utero CRISPR reach to lung diseases
Remember when researchers applied CRISPR to edit genes of mice fetuses while they are still in the womb, sparing them from death by liver disease? The same team from the University of Pennsylvania has now tested the same idea — albeit with a different technique — in genetic lung diseases.
In the burgeoning world of gene editing spawned by CRISPR, in utero treatment can be seen as a midpoint between early embryo editing (which passes the genetic alterations to future generations) and editing after birth, which can be too late for patients with certain lethal diseases.
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