Pfiz­er spells out PhI­II ta­la­zoparib da­ta in NE­JM ar­ti­cle; Tolero teams up with Ab­b­Vie for AML com­bo

David Hung of­fered a hard sell of his ex­per­i­men­tal PARP drug ta­la­zoparib while bid­ders lined up in what turned out as a $14 bil­lion Medi­va­tion buy­out by Pfiz­er. Now re­searchers are spelling out all the da­ta in an ar­ti­cle in the New Eng­land Jour­nal of Med­i­cine as Pfiz­er lines up a quick re­view and like­ly OK for a drug that will face some well en­trenched com­peti­tors.

→ Salt Lake City-based Tolero Phar­ma­ceu­ti­cals has struck a deal to share the costs on an up­com­ing com­bo can­cer drug tri­al with Ab­b­Vie. Re­searchers will match Tolero’s alvo­cidib, a CDK9 drug, with Ab­b­Vie’s vene­to­clax for treat­ment re­sis­tant cas­es of acute myeloid leukemia.

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