Phase­Bio de­tails dol­lars in As­traZeneca deal as it rolls out a plan for $86M-plus IPO

It turns out the $34 mil­lion Se­ries D Phase­Bio an­nounced just days ago was a pre­lude to a big­ger sto­ry: With its new­ly honed or­phan dis­ease-fo­cused strat­e­gy, the biotech is an­gling for an IPO worth at least $86 mil­lion.

The main draw re­mains PB2452, a re­ver­sal agent for the blood thin­ner Bril­in­ta (tica­grelor) for use in acute sit­u­a­tions where pa­tients are ex­pe­ri­enc­ing ac­tive bleed­ing or re­quire ur­gent surgery. Phase­Bio li­censed the drug — al­so known as an an­ti-an­ti-co­ag­u­lant — late last year from Med­Im­mune with­out dis­clos­ing the terms; we now know the deal is heav­i­ly back-end­ed with an up­front fee of on­ly $100,000 and $68 mil­lion in to­tal po­ten­tial mile­stones.

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