Pin­cer move­ment: Cal­i­for­nia biotech gets $35M to suf­fo­cate can­cer in co­or­di­nat­ed at­tack

Hav­ing served in Afghanistan, the navy vet­er­an lead­ing Cal­i­for­nia-based Epi­cen­tRx wants to leave no pa­tient be­hind with his ar­se­nal of an­ti-can­cer drugs. On Thurs­day, the com­pa­ny was giv­en a $35 mil­lion boost to fur­ther its mis­sion.

The in­jec­tion of funds will be used to shep­herd its late-stage CD47 drug, RRx-001, to the FDA for mar­ket­ing, and its on­colyt­ic virus pro­gram in­to the clin­ic.

RRx-001, en­gi­neered as an agent that makes tu­mor cells more sen­si­tive to ther­a­py, is in a Phase III tri­al in com­bi­na­tion with chemother­a­py for use in third-line and be­yond small cell lung can­cer (SCLC). The drug has been grant­ed or­phan drug des­ig­na­tion from FDA for SCLC, neu­roen­docrine can­cer and glioblas­toma.

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