Roche pulls a tu­mor mi­cro-en­vi­ron­ment drug out of the freez­er, hands it to a UK up­start

Two years af­ter pulling it from clin­i­cal de­vel­op­ment, Roche has hand­ed con­trol of a sol­id tu­mor can­cer drug to a tiny Ox­ford Uni­ver­si­ty spin­out.

For an undis­closed fee, Celleron Ther­a­peu­tics ac­quired the drug, an an­ti-CSF1R an­ti­body that’s de­signed to mod­u­late the tu­mor mi­cro-en­vi­ron­ment — an in­creas­ing­ly pop­u­lar ap­proach among can­cer drug de­vel­op­ers. Celleron says it will now put the drug in­to tri­als for pa­tients with tenosyn­ovial gi­ant cell tu­mors, a rare dis­ease where se­ries of be­nign tu­mors be­gin to grow around the joints and ten­dons. It’s caused by cells over-pro­duc­ing CSF1R.

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