Roche’s new flu drug con­tin­ues to rack up PhI­II suc­cess­es — but can it beat gener­ic Tam­i­flu with out­comes like this?

Roche’s cam­paign to cre­ate a suc­ces­sor to Tam­i­flu took one step for­ward to­day with the news that Xofluza was well tol­er­at­ed in chil­dren tak­ing the flu med. But once again it’s “com­pa­ra­ble” to Tam­i­flu, the fran­chise drug at Roche that’s been shred­ded by copy­cat ri­vals since the drug came off patent.

And that could be two steps back.

We won’t get the hard num­bers on MIN­I­S­TONE-II un­til lat­er, but Roche’s bot­tom line here is that Xofluza is just as good as the world’s lead­ing an­tivi­ral med, now avail­able cheap. That leaves Roche mak­ing the case that the one-dose reg­i­men for Xofluza is eas­i­er and more cer­tain to do the job, avoid­ing the risk of pro­long­ing the flu — which can be dan­ger­ous — and see­ing it spread fur­ther and faster if the dos­ing isn’t com­plet­ed prop­er­ly.

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