Strike two: Vi­cal says an­oth­er one of its vac­cines has crashed and burned in PhII

An­oth­er de­vel­op­ment pro­gram has run up on­to the rocks at Vi­cal $VI­CL.

Five months af­ter the San Diego-based biotech was forced to re­struc­ture in the af­ter­math of a crit­i­cal Phase II fail­ure, one of the two clin­i­cal pro­grams it turned to in the wake of that set­back has al­so been scrapped. And the fresh fail drove its shares down 29% be­fore the open.

Re­searchers say that their bi­va­lent vac­cine can­di­date for her­pes sim­plex virus type 2 failed to beat a place­bo on the re­cur­rence of le­sions among 261 pa­tients re­cruit­ed for the study. And like the CMV vac­cine ASP0113, the biotech is opt­ing to wash its hands of the whole ef­fort now.

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