Strug­gling Heat gets a warm re­sponse to a snap­shot on can­cer vax da­ta

Heat Bi­o­log­ics man­aged to at least tem­porar­i­ly ex­tri­cate it­self from pen­ny stock ter­ri­to­ry af­ter of­fer­ing a pos­i­tive up­date on its com­bi­na­tion study for non-small cell lung can­cer. Its stock surged more than 20% this morn­ing based on an up­date for a hand­ful of pa­tients tak­ing a com­bi­na­tion of HS-110 and Bris­tol-My­ers Squibb’s check­point in­hibitor Op­di­vo.

The up­dat­ed snap­shot from the Durham, NC-based biotech in­clud­ed a note that 3 of 5 pa­tients en­rolled in a co­hort for low tu­mor in­fil­trat­ing lym­pho­cytes “ex­pe­ri­enced sig­nif­i­cant tu­mor re­duc­tion, which is high­er than the 10% re­sponse rate of low TIL pa­tients re­port­ed for ex­ist­ing da­ta on nivolum­ab alone.” 5 of 12 evalu­able pa­tients ex­pe­ri­enced an im­mune re­sponse to the com­bo.

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