Can you cut $600M in R&D costs with­out slash-and-burn tac­tics? Andy Plump aims to show us how

Big bio­phar­ma merg­ers have been out of fa­vor in the in­dus­try for close to a decade now, soured by the large scale de­struc­tion that at­tend­ed deals like the 2009 Wyeth buy­out by Pfiz­er, which was fol­lowed by slash and burn tac­tics that played hav­oc with re­search teams.

Now, years af­ter the bolt-on ac­qui­si­tion be­came a stan­dard fea­ture at the largest bio­phar­mas, which large­ly swore off ma­jor merg­ers, Take­da’s ex­ec­u­tive team has set a goal for it­self to see if a 237-year-old bio­phar­ma com­pa­ny based in Japan can in­te­grate two large re­search groups in­to a sin­gle glob­al net­work fo­cused heav­i­ly in the Cam­bridge/Boston hub — and use the big­ger op­er­a­tion to cat­a­pult them in­to the league of glob­al heavy­weights.

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