The class of mol­e­cules be­hind one of biotech's biggest Alzheimer's fail­ures gets a new lease on life

De­n­o­vo Bio­phar­ma has spent the last decade try­ing to res­ur­rect drugs that failed at oth­er com­pa­nies, but it had nev­er wad­ed in­to a class of mol­e­cules that failed quite as spec­tac­u­lar­ly as 5HT6 sero­tonin, an oft-failed shot on goal in Alzheimer’s. But, in the wake of Bio­gen’s de­rid­ed suc­cess with ad­u­canum­ab, all op­tions ap­pear back on the ta­ble.

On Thurs­day, the San Diego-Chi­nese biotech an­nounced it’s li­censed the once-aban­doned Alzheimer’s drug idalopir­dine from Lund­beck for an undis­closed fee.

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