The di­a­betes 'cure' Ver­tex ac­quired in its 2019 Sem­ma buy­out? It's head­ed to the clin­ic

The stem cell-de­rived ther­a­py at the cen­ter of Ver­tex’s $950 mil­lion buy­out of Sem­ma Ther­a­peu­tics in 2019, one that fea­tures promi­nent­ly in the com­pa­ny’s over­all cell and gene ther­a­py push, is one step clos­er to reach­ing the clin­ic.

Ver­tex is ex­pect­ed to launch a Phase I/II tri­al in the first half of this year af­ter the type 1 di­a­betes treat­ment re­ceived IND clear­ance from the FDA on Thurs­day, the com­pa­ny an­nounced. The pro­gram, dubbed VX-880, will be eval­u­at­ed in type 1 di­a­betes pa­tients with se­vere hy­po­glycemia and those who strug­gle to per­ceive the on­set of hy­po­glycemia, like young chil­dren.

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