The sec­ond, first AI de­vel­oped drug en­ters the clin­ic; Aprea gets break­through sta­tus for myelodys­plas­tic syn­dromes drug

Sum­it­o­mo Dainip­pon Phar­ma and the UK-based AI start­up Ex­sci­en­tia are claim­ing to have brought the first AI-de­signed drug in­to the clin­ic. The two com­pa­nies say they de­vel­oped the mol­e­cule in less than 12 months, as Ex­sci­en­tia’s AI rapid­ly gen­er­at­ed and sift­ed through mil­lions of po­ten­tial com­pounds to iden­ti­fy ones that would fit Sum­i­mo­to’s tar­get, a re­cep­tor in the brain as­so­ci­at­ed with OCD.

The pair are not the first to make such a claim. Re­cur­sion Bio billed it­self as the first AI com­pa­ny to en­ter hu­man tri­als in Ju­ly, al­though crit­ics point­ed out – and Re­cur­sion CEO Chris Gib­son read­i­ly con­ced­ed — that one of the drugs orig­i­nal­ly came out of the lab of co-founder Dean Li, now head of trans­la­tion­al re­search at Mer­ck. Paul Work­man, CEO of the UK’s In­sti­tute of Can­cer Re­search ap­peared to al­lude to Gib­son and this cri­tique in a quote he pro­vid­ed to Ex­sci­en­tia’s press team to dis­trib­ute to the me­dia: “This is very dif­fer­ent from the use of AI to re­pur­pose drugs,” he said.

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