UCB flash­es the da­ta be­hind its pos­i­tive pso­ri­a­sis read­outs. Can it com­pete in a crowd­ed field?

Eight months af­ter UCB an­nounced that a lit­tle-watched drug can­di­date out­per­formed J&J’s block­buster Ste­lara, the Bel­gian phar­ma is out with full da­ta that one in­ves­ti­ga­tor calls “re­mark­able.”

In the Phase III tri­al, 58.6% of pa­tients who took UCB’s IL-17 block­er bimek­izum­ab were com­plete­ly cleared of skin le­sions af­ter 16 weeks, com­pared to 20.9% of pa­tients on Ste­lara. The UCB drug al­so out­per­formed Ste­lara at how many pa­tients were clear af­ter one year and at less­er bench­marks for plaque clear­ance, with more than 8 out of 10 pa­tients show­ing 90% im­prove­ment, com­pared to rough­ly half on Ste­lara.

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