Ver­tex buys the top spot on the list of the biggest pre­clin­i­cal M&A deals. Were they robbed or was it a steal?

The odds of suc­cess for the av­er­age pre­clin­i­cal drug pro­gram are grim, as every­one in R&D can tell you. But that hasn’t stopped the deals in this space from gob­bling up more and more cash.

Ver­tex’s $950 mil­lion cash deal to buy Sem­ma and its pre­clin­i­cal stem cell pro­gram for di­a­betes — shoot­ing for a po­ten­tial cure that com­bines in­sulin-pro­duc­ing cells in­side a “tea bag” tech for pre­vent­ing them from spark­ing an im­mune re­sponse — shot straight to the top of the list of the biggest ac­qui­si­tions of pre­clin­i­cal as­sets over the past decade.

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