What does the past gen­er­a­tion of fail­ure in Alzheimer’s R&D look like in one slide?

Just how bad is it in the Alzheimer’s R&D are­na?

IQVIA just put to­geth­er some­thing of an im­pres­sion­ist piece on the slew of tri­al fail­ures record­ed over the years (be­low).

Ex­cept for one pop in 2014 — for a de­men­tia drug, Namzaric — there’s noth­ing by way of an FDA ap­proval go­ing back to 2002, 17 years of fail­ure and dis­as­ter, with Eli Lil­ly, Pfiz­er, J&J and oth­ers go­ing over the amy­loid be­ta cliff. That’s made the big play­ers leery of this field, but the prospect of be­ing the on­ly sig­nif­i­cant ther­a­py on the mar­ket for mil­lions of pa­tients con­tin­ues to fu­el the dri­ve to­ward some­thing — any­thing — to throw against the dis­ease.

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