What fail­ure? Cataba­sis shares soar af­ter ex­ecs tout open-la­bel da­ta, PhI­II plans

Be­fore re­view­ing Cataba­sis’ sec­ond at­tempt at mak­ing a good first im­pres­sion with its Phase II study of the Duchenne mus­cu­lar dy­s­tro­phy drug edasa­lonex­ent (CAT-1004), it’s im­por­tant to re­mem­ber what hap­pened the first time around.

It flopped — bad­ly — at help­ing pa­tients, as re­searchers re­port­ed in ear­ly Feb­ru­ary.  The drug failed to reg­is­ter a sig­nif­i­cant bio­mark­er ef­fect on mus­cle in­flam­ma­tion, look­ing very much like the place­bo. And its stock $CATB was shred­ded.

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