Michael Ehlers (Replicate)

With a fresh $75M, Michael Ehler­s' lat­est take on non-vi­ral gene ther­a­py is ready for take­off

When Michael Ehlers hit the ex­it at Bio­gen a few years ago to be­come a ven­ture part­ner at ATP, he al­so took the lead at a gene ther­a­py start­up called Lime­light Bio. Like many oth­ers in pur­suit of gene ther­a­py 2.0, the com­pa­ny was work­ing on non-vi­ral de­liv­ery ap­proach­es. And one pi­lot pro­gram re­al­ly stuck with him.

The sci­en­tists won­dered whether they could make a ful­ly syn­thet­ic DNA that would have “all the ver­sa­til­i­ty of not be­ing a vi­ral-based DNA,” but with su­pe­ri­or prop­er­ties.

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