Zyner­ba goes in­to melt­down mode as cannabis-de­rived drug flops in PhII

Two years af­ter its IPO, De­von, PA-based Zyner­ba Phar­ma­ceu­ti­cals $ZYNE is grap­pling with the fall­out from a failed Phase II study of its lead drug — a cannabis-de­rived ther­a­py de­liv­ered via a skin patch.

Re­searchers failed to find a re­al ben­e­fit for epilep­sy pa­tients in the tri­al, miss­ing on two dos­es in an at­tempt to re­duce fo­cal seizures over a place­bo.

The biotech’s shares were blitzed by the im­me­di­ate re­sponse from in­vestors, who drove the com­pa­ny’s shares down 63%.

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