The checkpoint frenzy in the immuno-oncology sphere has largely focused on blocking the ligand-receptor duo of PD-L1 and PD-1, which cancer cells use to shield themselves from the immune system. Dissatisfied by the ability of PD-L1 agents to go after aggressive, metastatic cancers, a group of UCSF researchers are charting a new path: What if … Continue reading Blocking PD-L1 production in mice, UCSF team spotlights preclinical promise of a Pfizer-backed I/O drug