Incyte flips China rights of MacroGenics' PD-1 to an ambitious Zai Lab keen on leapfrogging pioneers with combos
Amid the proliferation of checkpoint inhibitors in China, Zai Lab is bringing in one more PD-1 agent in a move to install what has become an essential part of any immuno-oncology pipeline.
Originally developed by MacroGenics and now controlled by Incyte, INCMGA0012 is in Zai Lab’s view a globally competitive asset that can stand as both a monotherapy and combination ingredient.
“The molecular profile is quite similar to Keytruda and Opdivo,” said Yongjiang Hei, Zai Lab’s CSO in oncology, on an investor call.
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