Cyanotriazole binds to the DNA cleavage site of Trypanosoma cruzi Topoisomerase II via a covalent bond with a cysteine residue. (Andreas Schenk)
Novartis-led group develops new class of antiparasitic drug targeting diseases caused by trypanosomes
Trypanosomes look like microscopic one-celled eels, but instead of water, some of the parasites swim in blood and others dive in and out of cells …
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