A bruised Cir­cas­sia of­floads debt by re­turn­ing COPD drugs to As­traZeneca

It had a glit­ter­ing £200 mil­lion mega-IPO on the Lon­don Stock Ex­change in 2014, but fail­ure af­ter tri­al fail­ure blight­ed its prospects. A bat­tered Cir­cas­sia Phar­ma­ceu­ti­cals, by 2017 re­liant on its asth­ma man­age­ment de­vice Niox for rev­enue, turned to fel­low UK drug­mak­er As­traZeneca to in­fuse some oxy­gen in­to its starved pipeline.

The com­pa­nies joined forces in an up to $300 mil­lion deal to de­vel­op and mar­ket Tu­dorza and Du­ak­lir, two of As­traZeneca’s chron­ic ob­struc­tive pul­monary dis­ease drugs, in the Unit­ed States. On Thurs­day, Cir­cas­sia hand­ed the two ap­proved drugs back to As­traZeneca.

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