A Jennifer Doudna-led team finds a new CRISPR enzyme in the giant viruses of a California mud bog
A team led by UC Berkeley’s Jennifer Doudna has found a new CRISPR enzyme in an unlikely place: Viruses.
CRISPR, the gene-editing system that’s unleashed a revolution in biomedical research, was first reverse-engineered from a system bacteria evolved over eons to defend themselves from viruses. So viruses may sound like a strange place for CRISPR to show up. But the pathogens Doudna were studying belonged to a particular kind of viruses that researchers are just uncovering: Huge phages – massive viruses that feed on bacteria.
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