Andrew Kruegel, Kures president and co-founder (Columbia Tech Ventures via Vimeo)

Af­ter psilo­cy­bin and ke­t­a­mine, a new biotech comes along de­vel­op­ing a drug Scott Got­tlieb fought

An­drew Kruegel was six years in­to his chem­istry work at Co­lum­bia Uni­ver­si­ty, when, one day in Au­gust 2016, he learned he might have on­ly 30 days be­fore the gov­ern­ment made him de­stroy his re­search.

Kruegel had been study­ing kratom, a leaf long used in South­east Asia as a stim­u­lant or for pain. It had opi­oid-like prop­er­ties, he found, but seemed to of­fer pain re­lief with­out the ad­dic­tive po­ten­tial or res­pi­ra­to­ry side ef­fects of tra­di­tion­al opi­oids — a rid­dle that might help il­lu­mi­nate how hu­man opi­oid re­cep­tors work.

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