Anxious to fill Humira-sized revenue hole ahead of US patent cliff, AbbVie hits the ground running with FDA approval for Skyrizi
With the looming cloud of losing US patent protection for its mega-blockbuster Humira, AbbVie needs all the help it can get to fill the gaping $20 billion hole the flagship autoimmune disease drug will leave in its coffers. On Tuesday, the company secured the FDA approval of an IL-23 inhibitor, Skyrizi, that is expected to go some way in replenishing that revenue stream: $4 billion to $5 billion in peak annual sales by AbbVie’s estimate — although that may be difficult in the intensely competitive field it is set to enter.
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