Ar­cel­lx's cell ther­a­py is on hold af­ter pa­tient death in mul­ti­ple myelo­ma tri­al

Ar­cel­lx said its au­tol­o­gous cell ther­a­py was put on hold last Fri­day af­ter the death of a re­cent pa­tient in a tri­al test­ing the biotech’s CAR-mod­i­fied T cell ther­a­py in re­lapsed or re­frac­to­ry mul­ti­ple myelo­ma.

The hold im­pacts Ar­cel­lx’s lead pro­gram, which is al­so part of Gilead’s bet that it can com­mer­cial­ize ad­di­tion­al cell ther­a­pies fol­low­ing the suc­cess of its Kite unit. The bio­phar­ma con­tributed $225 mil­lion up­front on the pro­gram late last year, around the time ini­tial da­ta came out at the an­nu­al Amer­i­can So­ci­ety of Hema­tol­ogy meet­ing.

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