Pascal Touchon, Atara CEO

ASH: With PhI­II da­ta in hand, Atara eyes a sub­mis­sion to treat a small but des­per­ate group of trans­plant pa­tients

Af­ter more than two decades in the clin­ic, Atara Bio­ther­a­peu­tics’ T cell ther­a­py tab­ele­cleu­cel is fi­nal­ly head­ed to the FDA — but not with­out a piv­otal read­out at this year’s ASH con­fer­ence.

About half of pa­tients re­spond­ed to tab-cel, Atara’s can­di­date for Ep­stein-Barr virus-pos­i­tive post-trans­plant lym­pho­pro­lif­er­a­tive dis­ease (EBV+ PTLD), a rare com­pli­ca­tion that can oc­cur af­ter sol­id or­gan or hematopoi­et­ic stem cell trans­plant.

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