Samit Hirawat, Bristol Myers Squibb CMO

#ASH22: Bris­tol My­ers re­ports next-gen CAR-T da­ta as ri­val’s bis­pe­cif­ic heads to FDA, and gives al­nuc­tam­ab an­oth­er shot

NEW OR­LEANS — Bris­tol My­ers Squibb pulled back the cur­tain on its CAR-T cell ther­a­py go­ing af­ter GPRC5D, and al­so re­leased Phase I da­ta for its BC­MA-CD3 bis­pe­cif­ic al­nuc­tam­ab an­oth­er go.

Both da­ta drops are in pa­tients with re­lapsed/re­frac­to­ry mul­ti­ple myelo­ma.

Bris­tol My­ers’s au­tol­o­gous CAR-T cell ther­a­py is called BMS-986393/CC-95266, and it tar­gets GPRC5D, which is high­ly ex­pressed on mul­ti­ple myelo­ma cells. John­son & John­son’s Janssen unit has a ri­val treat­ment.

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