Astellas pursues ‘convertible’ in vivo CAR-T cell therapies with Kelonia Therapeutics
Astellas is penning a deal with Kelonia Therapeutics to develop in vivo cell therapies to treat cancer, but with a twist.
Not only would the treatments be off-the-shelf, meaning that they would not have to be tailored to each patient as current CAR-T therapies are, but the two companies plan to engineer them to be “convertible” — the CAR-T cells could be turned on and off using an antibody.
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