As­traZeneca, Dai­ichi Sankyo’s En­her­tu claims an­oth­er Phase 3 vic­to­ry in HER2-low breast can­cer

En­her­tu notched an­oth­er win for As­traZeneca and Dai­ichi Sankyo that could see up­take moved slight­ly ear­li­er in a spe­cif­ic sub­set of breast can­cer pa­tients.

The Phase 3 DES­TINY-Breast06 study set En­her­tu against chemother­a­py. The ADC hit the pro­gres­sion-free sur­vival pri­ma­ry end­point in the pri­ma­ry tri­al pop­u­la­tion of HR-pos­i­tive breast can­cer pa­tients who are low on HER2, or the hu­man epi­der­mal growth fac­tor re­cep­tor 2, and have gone through one or more lines of en­docrine ther­a­py.

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