As­traZeneca stops PhI­Ia tri­al of in­haled asth­ma drug with Pieris, cra­ter­ing the Boston biotech's shares

Af­ter culling a HER2 drug last sum­mer to fo­cus on an in­haled asth­ma med with As­traZeneca, Pieris Phar­ma­ceu­ti­cals ap­pears to be on thin ice with that pro­gram as well, as the Big Phar­ma end­ed a Phase IIa tri­al.

As­traZeneca in­formed Boston-based Pieris yes­ter­day that it will scrap a Phase IIa study of elarek­ibep af­ter tak­ing a look at safe­ty find­ings from a non-clin­i­cal tox­i­col­o­gy study. The dry pow­der in­haled for­mu­la­tion is al­so known as PRS-060/AZD1402 and is an IL-4 re­cep­tor al­pha in­hibitor.

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