Adam Simpson, Icosavax CEO

As­traZeneca plunks down $800M+ up­front to buy vac­cine de­vel­op­er Icosavax and chal­lenge Pfiz­er, GSK in RSV

As­traZeneca is shelling out $838 mil­lion up­front to ac­quire Icosavax and its pro­tein virus-like par­ti­cle plat­form tech­nol­o­gy in a move to add mus­cle to the Big Phar­ma’s vac­cine R&D group.

The buy­out al­so vaults As­traZeneca to a po­si­tion where it can chal­lenge Pfiz­er and GSK in the vac­cine mar­ket for res­pi­ra­to­ry syn­cy­tial virus, or RSV. As­traZeneca al­ready counts two pre­ven­ta­tive RSV an­ti­bod­ies in its port­fo­lio — Synagis and Bey­for­tus — mar­ket­ed via part­ner­ships with Sanofi and So­bi. But it will now get its hands on Icosavax’s Phase III-ready bi­va­lent vac­cine can­di­date against both RSV and hu­man metap­neu­movirus (hM­PV).

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