As­traZeneca's Ul­tomiris hits pri­ma­ry end­point for PhI­II NMOSD study

As­traZeneca caught a trio of re­cent wins — scor­ing an ex­pand­ed in­di­ca­tion for its breast can­cer drug En­her­tu, nail­ing Farx­i­ga’s Phase III win ear­li­er this week, and now, an­oth­er tri­al win.

The UK phar­ma said Thurs­day that its long-act­ing C5 com­ple­ment in­hibitor drug Ul­tomiris (ravulizum­ab-cwvz) hit on its pri­ma­ry end­point in the Phase III CHAM­PI­ON-NMOSD study. That end­point was to show a “sta­tis­ti­cal­ly sig­nif­i­cant and clin­i­cal­ly mean­ing­ful re­duc­tion in the risk of re­lapse in adults” with a spe­cif­ic type of a rare au­toim­mune dis­ease that tar­gets the cen­tral ner­vous sys­tem.

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