Kathy Bowdish, PIC Therapeutics CEO

Backed by Or­biMed, Sanofi vet's start­up tack­les the many mu­ta­tions of breast can­cer at once

In Rata­touille, Re­my the rat con­trols a young cook from his chef’s hat, di­rect­ing his every move in the restau­rant kitchen and help­ing him make food. Well, mes­sen­ger RNAs have a Re­my too.

Cap-bind­ing pro­teins that bind to one end of RNA se­quences di­rect how they are spliced and trans­lat­ed in­to pro­teins. In par­tic­u­lar, the pro­tein eIF4E binds to mR­NA caps and guides trans­la­tion (the eIF stands for eu­kary­ot­ic trans­la­tion ini­ti­a­tion fac­tor).

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